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Several transmission research demonstrated a statistically significant adverse association between condom use and risk of HIV infection, whereas others did not. Determining the true extent to which condoms scale back risk is difficult because investigators have used various scales for describing condom use. Because so few people apply oral-penile sex to the exclusion of other sexual practices, it is very tough to recruit and retain topics for epidemiologic research of the HIV threat associated with this apply. Only one study was ready to do that ; another examined monogamous serodiscordant couples whose solely unprotected sexual exercise was oral sex.